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Last Updated: Aug 03, 2026

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Nursing ACNS Practice Q&A's

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Nursing ACNS Exam Syllabus Topics:

SectionObjectives
Evidence-Based Practice and Research- Translation of research into clinical practice
  • 1. Implementation of best practices
    • 2. Critical appraisal of evidence
      Systems Leadership and Quality Improvement- Healthcare systems improvement
      • 1. Quality and safety initiatives
        • 2. Policy and regulatory compliance
          Professional Role Development- Advanced practice nursing roles and ethics
          • 1. Ethical and legal considerations in CNS practice
            • 2. Interprofessional collaboration
              Patient and Family Outcomes Management- Care coordination and chronic disease management
              • 1. Population-focused care strategies
                • 2. Patient education and self-management support
                  Clinical Judgment and Advanced Practice Nursing- Comprehensive health assessment and differential diagnosis
                  • 1. Physical assessment across adult populations
                    • 2. Clinical reasoning and diagnostic interpretation

                      Nursing ANCC Adult Health Clinical Nurse Specialist Certification (ACNS) Sample Questions:

                      1. At what point should a chest tube be removed?

                      A) mid expiration.
                      B) end of expiration.
                      C) beginning of expiration.
                      D) maximal inspiration.


                      2. A patient who has normocytic anemia may MOST likely also have a history of which condition?

                      A) Abnormal lipid levels.
                      B) Rheumatoid arthritis.
                      C) Osteoarthritis.
                      D) Upper respiratory infections.


                      3. There are several stages in the Trans-Theoretical Model of Change proposed by Prochashka and DiClemente, 1984. Which of the following is NOT one of the stages of change?

                      A) Preparation
                      B) Self-actualization
                      C) Action
                      D) Pre-contemplation


                      4. When treating a patient who has an extremely high P.T. level from coumadin (warfarin) usage, the ACNS understands that which of the following is the antidote?

                      A) Vitamin D
                      B) Vitamin K
                      C) Vitamin C
                      D) Vitamin A


                      5. You are treating your patient with a 5HT4 agonist for his gastrointestinal disorder. Of the following, which would you prescribe?

                      A) Senna.
                      B) Tegaserod.
                      C) Cisapride.
                      D) Alosetron.


                      Solutions:

                      Question # 1
                      Answer: D
                      Question # 2
                      Answer: B
                      Question # 3
                      Answer: B
                      Question # 4
                      Answer: B
                      Question # 5
                      Answer: B

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