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Last Updated: Aug 13, 2026

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Nursing ACNS Practice Q&A's

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Nursing ACNS Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Clinical Practice46%- Health Assessment and Diagnosis
- Evaluation of Outcomes
- Pharmacologic and Nonpharmacologic Management
- Health Promotion and Disease Prevention
- Care Planning and Implementation
Topic 2: APRN Core Competencies16%- Advanced Health Assessment
- Advanced Pathophysiology
- Advanced Pharmacology
Topic 3: Role and Professional Responsibility33%- Quality Improvement and Safety
- Evidence-Based Practice and Research
- Ethics and Legal Aspects
- Education and Mentorship
- Clinical Leadership and Consultation
Topic 4: Health Care Systems and Policy5%- Resource Management
- Regulatory and Policy Frameworks
- Healthcare Delivery Models

Nursing ANCC Adult Health Clinical Nurse Specialist Certification (ACNS) Sample Questions:

1. A sign of increased intracranial pressure is:

A) Opacity of the corneas.
B) Microvascularization and microaneurysms.
C) Optic disc swollen with blurred edges.
D) Copper and silver wire arterioles.


2. You are providing patient education to a female patient who has been diagnosed with herpes simplex 2. She asks about engaging in sexual activity and what type of precautions she must take to avoid infecting her male partner. Which of the following is an appropriate response to this patient?

A) The patient can engage in sexual activity without a condom as long as there are no lesions present.
B) The patient can engage in normal sexual activity at any time as long as she uses condoms.
C) The patient can engage in normal sexual activity as long as she uses condoms and refrains from sexual activity during an outbreak.
D) The patient must refrain from all sexual activity.


3. A 72-year-old male patient with longstanding hypertension takes an ACE inhibitor and a thiazide diuretic daily. Today his blood pressure is 128/88 and his pulse is 98. He has developed dyspnea on exertion and peripheral edema over the past several days. The ACNS knows that these symptoms demonstrate:

A) development of CHF
B) the need for better blood pressure management
C) fluid or sodium excess
D) noncompliance with medication


4. Your patient arrives in the Emergency Department displaying symptoms of acute coronary syndrome. The attending physician suspects ACS as well. Of the following, which is the appropriate intervention?

A) The patient should be given angina medication and sent home.
B) The patient should be admitted for observation.
C) The patient should receive a 12 lead EKG within 10 minutes of arrival.
D) The patient should receive a 12 lead EKG within an hour of arrival.


5. When caring for a patient nearing the end of life, it can sometimes be helpful to ask the patient about significant events and people in his or her life. This allows the patient to see the good he or she has done in life, to recall important memories, and to put his or her life in context. This exercise is known as which of the following?

A) Life review.
B) Life assessment.
C) Spiritual review.
D) Spiritual assessment.


Solutions:

Question # 1
Answer: C
Question # 2
Answer: C
Question # 3
Answer: A
Question # 4
Answer: C
Question # 5
Answer: A

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