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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 72-year-old woman with a long history of schizophrenia has been admitted to the state hospital because of a recent relapse while on risperidone 5 mg daily. It is decided to use an equivalent dose of ziprasidone. Which reference would most likely provide this information?

A) Martindale: The Complete Drug Reference
B) Diagnostic and Statistical Manual of Mental Disorders - V
C) The Sanford Guide
D) Drug Facts & Comparisons

2. An article in a clinical pharmacology journal describes a double-blind controlled trial comparing the efficacy of sumatriptan to a placebo injection for intractable migraine which used a 5 point Likert scale to evaluate headaches 2 hours after treatment. Which of the following is the most appropriate statistical test for analyzing the data?

A) Student's t test
B) Mann-Whitney U test
C) Chi-square test
D) Fisher's exact test

3. A 55 year old woman being treated for hypothyroidism with levothyroxine 125 mcg daily is currently euthyroid. She now has menopausal symptoms and is receiving conjugated estrogens.
What effect is this most likely to have on her thyroid function tests?

A) Decreased free T4
B) No changes in reverse triiodothyronine uptake
C) Decreased total T4
D) No changes in TSH

4. A patient with recently diagnosed Iymphoma is receiving doxorubicin, bleomycin, vinblastine, and dacarbazine. Aggressive intravenous hydration is required to decrease the complications associated with which of the following?

A) Tumor lysis syndrome
B) Bleomycin pulmonary toxicity
C) Doxorubicin cardiomyopathy
D) Dacarbazine nephrotoxicity

5. An investigator decides to perform a correlation analysis of the relationship between the number of cigarettes smoked per day and age. Results show a positive correlation between the two, with an r value of 0.50 and ap value for the correlation equal to 0.03. What is the most reasonable interpretation of this correlation?

A) There is no relationship between age and amount of smoking.
B) Increased age does not cause students to smoke more.
C) There is a statistically significant numerical association between age and amount of smoking.
D) Increased age causes students to Smoke more.

Solutions: