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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:
1. A 65-year-old woman on chronic hemodialysis presents with difficulty breathing and inability to sleep. The patient has had shortness of breath, diaphoresis, and nausea, but has not vomited.
She denies having abdominal pain, diarrhea, or chest pain. She has tachycardia and tachypnea, and exhibits peaked T waves with occasional PVCs on the ECG. Serum chemistry values are:
* Sodium: 137 mEq/L
* BUN: 125 mg/dL
* Potassium: 7.2 mEq/L
* Creatinine: 12.8 mg/dL
* Chloride: 97 mEq/L
* Glucose: 95 mg/dL
* HCO3- : 11 mEq/L
* Calcium: 8.5 mg/dL
* Albumin: 3.1 g/dL
* Phosphorus: 1.7 mg/dL
Which of the following should the pharmacotherapy specialist recommend for immediate therapy?
A) Hemodialysis
B) Sodium bicarbonate intravenously
C) Sodium polystyrene sulfonate with sorbitol orally
D) Calcium gluconate intravenously
2. A 45-year-old patient develops neutropenia, fever, headache, meningismus, and lethargy after induction chemotherapy for acute lymphocytic leukemia. A lumbar puncture reveals 1,000 total nucleated cells with elevated CSF protein with gram stain showing Gram-positive rods. Which of the following is the best initial empiric therapy for this patient?
A) Ceftriaxone
B) Ampicillin
C) Ceftazidime and gentamicin
D) Ampicillin and cefotaxime
3. In a clinical trial, when would "intention to treat" analysis be most appropriate?
A) Phase || trial
B) High drop-out rate
C) Crossover design
D) Small sample size
4. A drug use evaluation (DUE) of an institution's ACLS medication administration records yields the following data:
* Rate of amiodarone use in patients with asystole = 30%
* Rate of amiodarone use in patients with ventricular fibrillation = 90%
* Rate of epinephrine use in patients with pulseless electrical activity (PEA) = 98%
* Rate of vasopressin use in patients with pulseless ventricular tachycardia = 50% Which of the following treatments should be targeted for intervention?
A) Asystole
B) Pulseless electrical activity
C) Pulseless ventricular tachycardia
D) Ventricular fibrillation
5. A 47-year-old patient with end-stage renal disease undergoing hemodialysis has an HCT of 23% and exhibits anginal symptoms. Upon further Workup, no evidence of occult bleeding is found.
In addition to antianginal therapy, which of the following is the most appropriate initial treatment for this patient's anemia?
A) Subcutaneous erythropoietin
B) Oral iron
C) Iron dextran
D) Two units of PRBCs
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: A | Question # 3 Answer: D | Question # 4 Answer: A | Question # 5 Answer: D |
By Evangeline
