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Updated: Sep 10, 2026

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USMLE USMLE Exam Overview:

Certification Vendor:USMLE
Exam Name:United States Medical Licensing Examination
Exam Number:USMLE
Passing Score:Pass/Fail (Step 1)
Exam Price:USD 680
Available Languages:English
Certificate Validity Period:No fixed expiration; subject to individual state medical licensure requirements
Exam Format:Computer-based Examination, Single Best Answer Questions, Multiple Choice Questions (MCQs)
Exam Duration:480 (Step 1)
Real Exam Qty:Up to 280 (Step 1)
Related Certifications:USMLE Step 3
USMLE Step 1
USMLE Step 2 Clinical Knowledge (CK)
Sample Questions:USMLE USMLE Sample Questions
Exam Way:Computer-based examination administered at Prometric test centers worldwide.
Pre Condition:Applicants must meet eligibility requirements established by USMLE, including enrollment in or graduation from an accredited medical school recognized by the appropriate authorities.
Official Syllabus URL:https://www.usmle.org/

Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.

USMLE Step 3 is open to candidates who already hold their USMLE Step 1 and Step 2 certificates. Step 3 is a two-day exam that assesses whether candidates are able apply medical knowledge and understanding of biomedical and clinical science essential to unsupervised medical practice. This is the final USMLE exam which leads to the license to practice medicine without supervision - the ultimate goal of medical students and professionals willing to practice medicine in the United States. Step 3 represents the final assessment of physicians assuming independent responsibility for delivering general medical care.

USMLE United States Medical Licensing Examination

USMLE stands for United States Medical Licensing Examination. This is a series of medical exams coming in a few stages that all new doctors need to pass (starting from their time in med school) to be able to practice medicine.

USMLE Step 2 is a one-day (8 hours) exam. Similar to the Step 1, the test items are divided into blocks, and test item formats vary within each block, with the total number of exam questions equaling to 355.

Reference: http://www.usmle.org/step-1/#question-formats

USMLE USMLE Exam Syllabus Topics:

SectionObjectives
Endocrine System- Hormonal Regulation and Disease
  • 1. Thyroid Disorders
  • 2. Pituitary Disorders
  • 3. Adrenal Disorders
Gastrointestinal System- Digestive System Disorders
  • 1. Liver Disease
  • 2. Gastrointestinal Pathology
Human Development- Growth and Development
  • 1. Embryology
  • 2. Developmental Abnormalities
Renal and Urinary System- Kidney and Urinary Disorders
  • 1. Renal Pathology
  • 2. Renal Physiology
Respiratory System- Pulmonary Medicine
  • 1. Airway Disorders
  • 2. Lung Diseases
Musculoskeletal System- Bones, Joints, and Muscles
  • 1. Rheumatologic Diseases
  • 2. Orthopedic Disorders
Multisystem Processes and Disorders- Systemic Conditions
  • 1. Infectious Diseases
  • 2. Nutrition
  • 3. Neoplasia
General Principles- Foundational Medical Sciences
  • 1. Behavioral Sciences
  • 2. Pathology
  • 3. Immunology
  • 4. Biochemistry
  • 5. Pharmacology
  • 6. Microbiology
  • 7. Physiology
  • 8. Genetics
Reproductive System- Male and Female Reproductive Health
  • 1. Reproductive Physiology
  • 2. Reproductive Disorders
Central and Peripheral Nervous Systems- Neurologic Disorders
  • 1. Neurologic Diseases
  • 2. Neuroanatomy
  • 3. Neuropathology
Hematopoietic and Lymphoreticular Systems- Blood and Immune Disorders
  • 1. Anemias
  • 2. Leukemias and Lymphomas
  • 3. Coagulation Disorders
Skin and Related Connective Tissue- Dermatologic Conditions
  • 1. Skin Neoplasms
  • 2. Inflammatory Skin Disorders
Cardiovascular System- Cardiac and Vascular Disorders
  • 1. Vascular Pathology
  • 2. Heart Disease

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