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ASCP ASCP-MLT Exam Overview:

ASCP ASCP-MLT Exam Syllabus Topics:

ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Conversion of only the slant to a pink color in a Christensen's urea agar slant is produced by bacterial species that have weak urease activity. The reaction in the slant to the right is often produced by Klebsiella species, as an example. Strong urease activity is indicated by conversion of the slant and the butt of the tube to a pink color, as seen in the tube to the left. The slant only reaction in the right tube may be seen early on if only the slant had been inoculated; however, with a strong urease producer, both the slant and the butt would turn.
Therefore, the reaction is dependent on the strength of urease activity. If the media had outdated for a prolonged period, either there would be no reaction or the appearance of only a faint pink tinge, either in the slant, the butt or both, again depending on the strength of urease production by the unknown organism.
The urease reaction seen in the Christensen's urea agar slant on the far right indicates:

A) Weak activity
B) Use of outdated medium
C) Strong activity
D) Slant only inoculated

2. Allergen-specific IgE, synthesized in response to allergens, becomes fixed to receptors on cellular membranes, especially those of basophils. If these receptor-bound IgE molecules are aggregated on re-exposure to specific allergen, both mast cells and basophils produce mediators that result in the allergic response. IgE-antigen interaction at the cell surface causes degranulation of cells and release of substances including: histamine, SRS-A, platelet activator, a kallikrein, and an eosinophil chemotactic factor. Basophils are the principal cells that bind IgE antibody while their number of receptor sites is proportional to serum IgE levels. Eosinophils are drawn to the site by the basophil chemotaxis mechanism, but are not the main cell which binds the IgE antibody.
Immunology
The mediator cells that bind MOST to IgE antibodies are:

A) Polymorphonuclear neutrophils
B) Macrophages
C) Eosinophils
D) Basophils

3. Triglyceride blood concentrations change significantly when you eat, as opposed to relatively stable levels of cholesterol, HDL, or LDL circulating in the blood. Whenever you eat a meal that contains fat, your triglyceride levels rise, which is why it is important to have a patient fast before the sample is collected.
Which of the following lipid results would be expected to be FALSELY elevated on a serum specimen from a non-fasting patient?

A) triglyceride
B) LDL (not calculated)
C) HDL
D) cholesterol

4. The correct set of patient data would be: Hgb A = 60%, Hgb S = 38%, Hgb A2 = 2%, Hgb F = 0% Patients with sickle cell trait commonly have Hgb A values between 40 and 60%, Hgb S values between 20 and 40% and Hgb A2 values between 2 and 3%.
A known sickle cell trait patient has a hemoglobin electrophoresis test performed. Which of the following hemoglobin percentage sets would most closely match this patient's diagnostic state?

A) Hgb A = 60%, Hgb S = 38%, Hgb A2 = 2%, Hgb F = 0%
B) Hgb A = 90%, Hgb S = 8%, Hgb A2 = 2%, Hgb F = 0%
C) Hgb A = 40%, Hgb S = 58%, Hgb A2 = 2%, Hgb F = 0%
D) Hgb A = 25%, Hgb S = 70%, Hgb A2 = 2%, Hgb F = 3%

5. Basophilic stippling is strongly associated with lead poisoning the lead toxicity can affect the bone marrow; causing this phenomenon.
Hematology
What is a prominent morphologic feature of lead poisoning:

A) Basophilic stippling
B) Hypersegmentation
C) Macrocytosis
D) Target cell

Solutions: